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An easier way to administer Metaraminol

Aguettant ready to administer pre-filled syringes

For prescribing information, click here

Adverse events should be reported. Reporting forms and information can be found at http://yellowcard.mhra.gov.uk/

Adverse events should also be reported to Aguettant Limited on +44 1275 463 691

To reduce the likelihood of Metaraminol medication error

Nearly one-third of medication errors cause an adverse drug event, increasing the likelihood of patient death[1].

It has been estimated that more than 237 million medication errors are made every year in England. Errors are made at every stage of the process, with over half (54%) made at the point of administration[1-2].

But what if the way you administer Metaraminol to a patient could reduce that risk?

Pre-filled syringes (PFS) are your less risky alternative to ampoules

Aguettant Metaraminol pre-filled syringes are ready-to-administer with minimal manipulations reducing the likelihood of microbial contamination during the injection sequence.

Aguettant's PFS replaces glass ampoules with robust polypropylene material. They could significantly reduce the risk of medication errors to support you in providing safer patient care[3].

Designed for single patient use

We’ve designed the Aguettant pre-filled syringe to be the correct strength and volume for single patient use. 

By using a pre-prepared syringe of Metaraminol, you may avoid the potential for multiple dosing from a single use ampoule.
 

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A  straightforward and ready-to-administer Metaraminol alternative

Medication errors can occur at any stage of the process, from the initial prescription right through to administration.

Aguettant Metaraminol pre-filled syringes reduce the number of steps where medication errors could occur. They support you with more straightforward infection prevention practices by being ready to administer in a sterile blister:

  • A luer compatible connecion for needle-free administration

  • Terminal sterilisation by autoclave following filling, labelling and blister packing

  • Individual blister packaging to maintain sterility of both the solution and the external surface of the syringe

3 Steps to Metaraminol pre-filled syringes

Request an appointment with an Aguettant Key Account Manager to receive an on-site demonstration of our Metaraminol PFS.

An Aguettant team member will confirm a date and time for the demonstration to suit you.

During your on-site demonstration you can find out more about our:

  • Instruction For Use Posters

  • Training videos

  • Service Level Agreement 

  • Conversion Management Plan 

  • Conversion Posters 

  • Product Information Leaflets 

  • Product Information Packs

“(Ensure) medicines are presented as pre-filled syringes or other 'ready-to-administer' preparations wherever possible."

Royal Pharmaceutical Society[4].

How Metaraminol pre-filled syringes support you

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Reduced risk of medical errors

Potentially pathogenic microorganisms contaminate over 6% of bolus drug injections hand-prepared during anaesthesia[5].


When drawn up from a 10mg ampoule, Metaraminol has many preparation steps, potentially increasing the risk of medication errors.
Compared to ampoules, pre-filled syringes reduce the number of steps where potentially fatal medication
errors could occur to:

  • Reduce the possibility of human error[3]

  • Reduce the risk of microbial contamination of IV drugs[6]

  • Eliminate needle-stick injuries[7]

Meet your environmental aims.
Metaraminol pre-filled syringes.

When transferring a patient from one location to another, you don’t need to draw up a Metaraminol injection as a precaution.

Reduce Metaraminol drug waste

Medication-related incidents are the most common type of preventable patient harm (25% of identified harm), meaning getting the medication right the first time shortens hospital stays and uses fewer resources. 

Prefilled syringes have been shown to reduce infections, meaningfully reducing environmental impact.
 

Reduce your use of resources

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Considering all components used in the preparation steps of ampoules, your switch to Metaraminol pre-filled syringes could reduce your overall plastic use and the amount of waste you send to incinerators.

Reduce plastic waste

“Everybody’s dream is a perfect healthcare system where there are no errors. It’s an impossible dream. So our job is just to make little steps, big steps, towards increasing safety.[11]

Consultant Anaesthetist, Imperial College Healthcare NHS Trust

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Request an appointment to see our PFS demonstration

To find out more about how our Metaraminol ready-to-administer pre-filled syringes can support you in providing excellent patient care, request an appointment now.

Simply fill in the form below, and an Aguettant team member will arrange a date and time to suit you.
 

References

References 1) Nanji KC, Patel A, Shaikh S, Seger DL, Bates DW. Evaluation of perioperative medication errors and adverse drug events. Anesthesiology. 2016; 124:25-34. https:// doi:10.1097/aln.0000000000000904. 2) Gariel C, Cogniat B, Desgranges F-P, Chassard D, Bouvet L. Incidence, characteristics, and predictive factors for medication errors in paediatric anaesthesia: a prospective incident monitoring study. Br J Anaesth. 2018;120:563-570. https:// doi:10.1016/j.bja.2018.01.005. 3) Litman RS. How to prevent medication errors in the operating room? Take away the human factor. Br J Anaesth. 2018:120:438e-440e. https:// doi:10.1016/j.bja.2017.12.001. 4) Royal Pharmaceutical Society. Professional guidance on the safe and secure handling of medicines. Appendix C: Operating theatres - supplementary guidance, 2018. https://www.rpharms.com/recognition/setting-professional-standards/safe-and-secure-handling-of-medicines/professional-guidance-on-the-safe-and-secure-handling-of-medicines (accessed 3/12/2020). 5) Gargiulo DA, Mitchell SJ, Sheridan J, et al. Microbiological contamination of drugs during their administration for anesthesia in the Operating Room. Anesthesiology 2016; 124; 785-794. 6) Makwana S, Basu B, Makasana Y, Dharamsi A. Prefilled syringes: An innovation in parenteral packaging. Int J Pharm Investig. 2011 Oct;1(4):200-6. doi: 10.4103/2230-973X.93004. PMID: 23071944; PMCID: PMC3465144. 7) European Agency for Safety & Health at Work. (2022) Directive 2010/32/EU - prevention from sharp injuries in the hospital and healthcare sector. Brussels, European Agency for Safety & Health at Work. https://osha.europa.eu/en/legislation/directives/council-directive-2010-32-eu-prevention-from-sharp-injuries-in-the-hospital-and-healthcare-sector 8) Adapa RM, Mani V, Murray LJ, Degnan BA, Ercole A, Cadman B, Williams CE, Gupta AK, Wheeler DW. Errors during the preparation of drug infusions: a randomized controlled trial. Br J Anaesth. 2012 Nov;109(5):729-34. doi: 10.1093/bja/aes257. Epub 2012 Jul 31. PMID: 22850220. 9) T. Woodcock. (2014) Syringe labelling in critical care areas. Association of Anaesthetists of Great Britain and Ireland. www.RCOA.ac.uk 10) Panagioti M, Khan K, Keers R, et al. Preventable Patient Harm across Health Care Services: Review and Meta-analysis (Understanding Harmful Care) July 2017 https://www.gmc-uk.org/-/media/documents/preventable-patient-harm-across-health-care-services_pdf-73538295.pdf (accessed 03/01/2023). 11) Aguettant. (2022) The use of pre-filled syringes in anaesthetics and pharmacy - video. Bristol, Aguettant.

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